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NATURE11 February 2010 Volume 463 Number 7282, pp 709 - 840Visit Nature online to browse the journal.Now available at http://links.ealert.nature.com/ctt?kn=215&m=34619632&r=NDA5MjY2MjAxMgS2&b=2&j=NjcxNTYwMzIS1&mt=1&rt=0Please note that you…