NATURE18 February 2010 Volume 463 Number 7283, pp 849 - 990Visit Nature online to browse the journal.Now available at http://links.ealert.nature.com/ctt?kn=226&m=34637012&r=NDA5MjY2MjAxMgS2&b=2&j=Njc1MzkzOTES1&mt=1&rt=0Please note that you…